Best and the use of each sanctified hero has an opposite one except for the HP and Morale ones. Example Critical has a counter of Resilience, Dodge counter is Hit Rating, Block counter is Break, Physical Attack has Physical Defense, Skill Attack has Skill Defense, and Magic Attack has Magic Defense. If an opponent uses Critical a lot it is their strength so one must counter it with the Resilience.
As stated before I believe all characters, and the formations have strengths and weaknesses. So to win PVP or any fight for that matter you need to counter the strengths and exploit the weaknesses of their formations and characters.
Also there is limits to the sanctified hero. Example the maximum of 15 is limit for Block, Dodge, Resilience, Break, and Morale. While the maximum for the others varies slightly they are higher numbers.
I've seen players who will make one attribute lower thinking the other ones will become stronger. Unsure if this is true, but do know that if a player puts all the sanctification towards one thing they are easy to defeat if you counter the right way. Not all characters are best fully loaded with critical if they have no hit rating one can raise their block to stop the hit in first place if they don't have any break and use resilience to stop the critical all together. Balance yet build more off their strengths from beginning found on the cards Tynon provides is what I think best.
Watching fights in CW does give people an idea of what does best, but have noticed players tend to copy them and suddenly everyone is using Maria, yet don't fully understand all there is about that hero.
I've found it is best to READ the cards Tynon has given us to see what each hero is best at and you can either build on it like I'm going to do or fill the weak spots. Example; Queen Brynhildr card states she is: Talent - Skill Resistant 30% to start. 25 Hit Rating, 20 Dodge. Skill Defense is high at start and Mage Defense is low. I put her in front to absorb the skill attacks many use the first round of fighting and build her Skill defenses up more. Plus build more on her Hit Rating and Dodge as she starts with these and I've seen when placing more on these it seems to be best. Each hero has different starting attributes and the cards show these and their weaknesses, right?
My opinions and I'll stick to them.